How to Assist the Body to Mount the Initial Immune Response?
The body needs to mount an immune defence by elevating IL1(Interleukin 1), IL6(Interleukin 6) and TNFalpha (tumor necrosis factor alpha), and then mount a TH1((T-helper1) response to clear up the virus. If the interferon (signalling protein) response is delayed, because of the many ways the virus has to block interferon; an interferon-mediated response (cytokine storm) can contribute to lung pathology and even death. Use of these integrative approaches depends on the individual person, their pre-existing conditions, whether the focus is on preventing or addressing a stage of the illness, whether boosting or modulating immunity is required, or whether fatigue, stress or sleep levels need to be targeted.
Anti-viral Herbals/Nutrients/Minerals for Covid 19
Elderberry, Astragalus, Andrographis, Golden Seal, Echinacea have been found effective in upper-respiratory viruses, and for other retro viruses. Elderberry has a high value of caffeic acid (3.6-12mg per 1000mg extract) which has an antiviral effect by binding to ACE2 to prevent attachment by the virus. (Elderberry is also present in 100- 150gms of sunflower seeds, prunes and dates. Mushroom Complexes such as shitake, maitake, cordyceps, and turkey tail all have an adaptogenic i.e balancing (T regulatory)response. In immune compromised people especially , the AHCC (Active Hexose Correlated Compound) proprietary extract of Shitake is beneficial. Vit C is essential for immunity (leucocyte and macrophage functions, neutrophil motility), as an antimicrobial, for breaking down (phagocytosis) of the virus and for interferon synthesis. Vit C , has been used (in China for this outbreak of Co-V2) intravenously for severe and critically patients, at levels of 1500mg 3-4 times per day. Oral buffered Vit C, forms part of the approach to manage a cytokine storm. Bio-flavinoids (which are protease inhibitors) preventing the coronavirus from gaining access via the ACE2 receptor on the cell. (Also see AUSSAN PDF on my webpage -which is a sanitiser with bioflavonoids, which has been tested to achieve a 4 log reduction ie 99.99% reduction of the Corona family of viruses. Let me know if you would like to purchase the product, and if you would like pickup or post).
Zinc inhibits the proteases that allow the Covid virus to gain entry into the cell via the ACE2 receptors.
Garlic improves the TH1 response- using stabilised garlic, or crushing and leaving for 10mins for max allicin conversion.
Tea Tree proprietary extract of 98 active ingredients.
Vit D levels are recommended to be between 100-150 nmol/L in an integrative model of health (As vit D conversion occurs with UVB rays which occur during the peak burning time of the day- supplementation is commonly used to bring these levels up. As a rough guide -if your shadow is longer than you -you aren’t converting vit D).
Nitric Oxide (can be indirectly induced) by precursors such as arginine, citrulline, carnitine formulations and green leafy vegies and beets, as nitrates; and has an impressive antiviral effect. IMPT to note that ingesting nitrates with a good healthy oral microbiome, enables nitrate conversion to nitric oxide. This does not occur when mouthwash disrupts the oral microbiome (which can be effectively addressed using herbal preparations and probiotics).
Healthy Gut maintenance
Disrupting the gut microbiome makes us more prone to infection. Gut probiotics have the ability to modulate inflammation by reducing the oxidative stress, and impacting tight junctions in the gut and increasing immunity. Various healing agents Glutamine, quercetin, bromelain, slippery elm, marshmallow, aloe vera, licorice, MSM etc In addition, nutrigenomic formulations which are potent activators of cell protective genes; and the anti-oxidant enzymes which are able to reduce oxidative stress associated with pulmonary fibrosis. SPM’s (specialized pro resolving mediators) extracted from fish oil, promote the resolution of inflammation, reduce pain, encourage pathogen clearance and mitigate pathological inflammation without suppressing the immune system.